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Altered organization of filamentous actin and microtubule cytoskeletons in melanoma cancer cells. Maximum intensity Z-projections (XY) demonstrating alterations in filamentous actin (magenta) and microtubule cytoskeletons (green). Immunofluorescence images of cells were captured using a Zeiss LSM 900 Airyscan 2. Compared with benign counterpart fibroblasts and melanocytes, highly malignant melanoma cells exhibit significant decreases in F-actin and microtubule network density.

Journal: ACS Nano

Article Title: Multiplexed Nanoscale Viscoelastic Mapping at Multiple Time Scales of Melanoma Cells as a Label-Free Cancer Biomarker

doi: 10.1021/acsnano.5c01873

Figure Lengend Snippet: Altered organization of filamentous actin and microtubule cytoskeletons in melanoma cancer cells. Maximum intensity Z-projections (XY) demonstrating alterations in filamentous actin (magenta) and microtubule cytoskeletons (green). Immunofluorescence images of cells were captured using a Zeiss LSM 900 Airyscan 2. Compared with benign counterpart fibroblasts and melanocytes, highly malignant melanoma cells exhibit significant decreases in F-actin and microtubule network density.

Article Snippet: Human primary epidermal melanocyte cells were obtained from ATCC (Cat. # PCS-200-013) and cultured in Dermal Cell Basal Medium (ATCC, Cat. # PCS-200-030) supplemented with Phenol Red (ATCC) and Adult Melanocyte Growth Kit (ATCC, Cat. # PCS-200-042).

Techniques: Immunofluorescence

The Sigmoidal Dose-Response Curve of WS, AL, and DOX on % viability of MCF7 and HFB4 Cells and their IC 50 after 48 hours.

Journal: Asian Pacific Journal of Cancer Prevention : APJCP

Article Title: The Synergistic and Anticancer Potential of Withania Somnifera (Ashwagandha) Ethanol Extract as an Adjuvant with Doxorubicin in MCF7 Breast Cancer Cell Line

doi: 10.31557/APJCP.2025.26.3.757

Figure Lengend Snippet: The Sigmoidal Dose-Response Curve of WS, AL, and DOX on % viability of MCF7 and HFB4 Cells and their IC 50 after 48 hours.

Article Snippet: Human breast cancer (MCF7), which is an invasive breast ductal carcinoma with luminal epithelial phenotype and normal human skin melanocyte (HFB4) cell lines; a model to study the complexity of cellular aging were acquired from the National Cancer Institute, Egypt (Source: ATCC).

Techniques: